Frameworks resources are intended for educational purposes only and are intended for healthcare professionals and/or payer representatives. They are not intended as, nor are they a substitute for, medical care, advice, or professional diagnosis. Healthcare professionals should use independent medical judgment when considering Frameworks educational resources. Those seeking medical advice should consult with a healthcare professional. Frameworks resources are not intended as reimbursement or legal advice. Users should seek independent, qualified professional advice to ensure their organization is in compliance with the complex legal and regulatory requirements governing healthcare services, and that treatment decisions are made consistent with the applicable standards of care. Frameworks is sponsored by Otsuka Pharmaceutical Development & Commercialization, Inc.