For Educational Purposes Only

Collaborative care in major depressive disorder (MDD) begins with you

Cardiovascular disease, diabetes, and cancer are common in patients with MDD and may negatively impact outcomes and contribute to higher health expenditures in this patient population.1,2 In the primary care setting, primary care physicians, who deliver the majority of care for patients with MDD, only identify about 50 percent of MDD cases.3 The implementation of a collaborative care model may help ensure that adequate systems are in place for efficient diagnosis, treatment, and follow-up for patients with depressive disorders.4

It is estimated that 16.2 percent of Americans will be affected with MDD during their lifetime.5

Patients with MDD are often underdiagnosed, undertreated, or treatment resistant, representing a significant unmet need in treatment.6-8

Frameworks in Health and Quality: Value of Collaborative Care in Major Depressive Disorder is a series of educational resources for healthcare stakeholders — including providers and payers who can choose to share resources with patients and their caregivers — that aims to:

  • Emphasize the importance of collaborative care
  • Enhance communication among all stakeholders
  • Support stakeholders with patient and caregiver educational materials
  • Emphasize patient wellness and adherence to treatment plans
  • Promote depression management, utilization of depression screening tools, appropriate referral to a mental health specialist, and quality measures

Evidence supports collaborative care for improving depression symptoms, adherence to treatment, response to treatment, and remission and recovery from depression.9 Our Frameworks in Health and Quality: Value of Collaborative Care in Major Depressive Disorder disease management program can complement your efforts by providing resources to key stakeholders who are in a position to help improve the quality of care delivered to patients.

  1. Katon WJ. Clinical and health services relationships between major depression, depressive symptoms, and general medical illness. Biol Psychiatry. 2003;54(3):216-226.
  2. Chapman DP, Perry GS, Strine TW. The vital link between chronic disease and depressive disorders. Prev Chronic Dis. 2005;2(1):1-10.
  3. Huang SH, LePendu P, Iyer SV, Tai-Seale M, Carrell D, Shah NH. Toward personalizing treatment for depression: predicting diagnosis and severity. J Am Med Inform Assoc. 2014;21(6):1069-1075.
  4. Medical Directors Institute of the National Association of Managed Care Physicians. Integrated care. Accessed April 21, 2015.
  5. Kessler RC, Berglund P, Demler O, et al. The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). JAMA. 2003;289(23):3095-3105.
  6. Chen SY, Hansen RA, Gaynes BN, Farley JF, Morrissey JP, Maciejewski ML. Guideline-concordant antidepressant use among patients with major depressive disorder. Gen Hosp Psych. 2010;32(4):360-367.
  7. Nierenberg AA. Current perspectives on the diagnosis and treatment of major depressive disorder. Am J Manag Care. 2001;7(suppl 11):S353-S366.
  8. Kubitz N, Mehra M, Potluri RC, Garg N, Cossrow N. Characterization of treatment resistant depression episodes in a cohort of patients from a US commercial claims database. PLoS One. 2013;8(10):e76882.
  9. Community Preventive Services Task Force. Recommendation from the community preventive services task force for use of collaborative care for the management of depressive disorders. Am J Prev Med. 2012;42(5):521-524.

Frameworks resources are intended for educational purposes only and are intended for healthcare professionals and/or payer representatives who may choose to share some of these resources with patients or their caregivers. Healthcare professionals should use independent medical judgment when considering Frameworks educational resources. Patients and caregivers should discuss Frameworks materials with a healthcare professional. They are not intended as, nor are they a replacement for, medical advice and treatment from a healthcare professional. Frameworks resources are not intended as reimbursement or legal advice. Users should seek independent, qualified professional advice to ensure their organization is in compliance with the complex legal and regulatory requirements governing healthcare services, and that treatment decisions are made consistent with the applicable standards of care. Frameworks is sponsored by Otsuka Pharmaceutical Development & Commercialization, Inc.